SCHEMBL937374

SCHEMBL937374

CC(C(N)=O)=C(C(=O)O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
MAPT P10636 3/20 0.48
CYP2C19 P33261 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CES2 O00748 4/20 0.45
CES1 P23141 4/20 0.45
PTGS1 P23219 1/20 0.45
GAA P10253 1/20 0.44
ALDH1A1 P00352 4/20 0.43
LMNA P02545 1/20 0.43
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937370 1.00 TSHR (0.48) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL14677026 0.89 TSHR (0.50) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL14677020 0.89 TSHR (0.50) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL29140470 0.86 CES2 (0.54) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL8466095 0.85 CES1 (0.50) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL8466096 0.85 CES1 (0.50) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL162761 0.85 CES1 (0.50) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL28198887 0.83 TSHR (0.52) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL4744670 0.80 TSHR (0.54) TSHRMAPTCYP2C19L3MBTL1POLB
SCHEMBL4744665 0.80 TSHR (0.54) TSHRMAPTCYP2C19L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1532566-B Radiation sensitive composition for color filter JSR CORP 2010-05-12 CN claimed
WO-2012054237-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND METHODS OF USE EASTMAN KODAK COMPANY (US) 2012-04-26 WO disclosed
US-20120090486-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND METHODS OF USE KODAK (NEAR EAST) INC. 2012-04-19 US disclosed
WO-2011009910-A1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER MADE OF A THERMOPLASTIC ELASTOMER AND LAMELLAR FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-01-27 WO disclosed
US-7452638-B2 Negative-working radiation-sensitive compositions and imageable materials EASTMAN KODAK COMPANY (US) 2008-11-18 US disclosed
WO-2008036170-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS EASTMAN KODAK COMPANY (US) 2008-03-27 WO disclosed
US-20080070152-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS BANK OF AMERICA, N.A., AS AGENT 2008-03-20 US disclosed