SCHEMBL9373786

SCHEMBL9373786

CC(C)(C)c1cc(CCC(=O)NN2C(=O)C3C4C=CC(C3C2=O)C2C(=O)N(NC(=O)CCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(=O)C42)cc(C(C)(C)C)c1O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.55
KMT2A Q03164 3/20 0.52
MAOB P27338 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAOA P21397 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.47
AGTR1 P30556 1/20 0.47
HTT P42858 1/20 0.47
PKM P14618 1/20 0.46
MEN1 O00255 2/20 0.46
ACHE P22303 1/20 0.45
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742555 0.87 GAA (0.53) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9743605 0.81 GAA (0.62) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9545502 0.80 GAA (0.60) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9743032 0.78 GAA (0.49) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9375800 0.75 GAA (0.54) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9376680 0.75 GAA (0.60) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL39122 0.74 GAA (0.77) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL20390741 0.74 GAA (0.70) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL9379388 0.74 GAA (0.52) GAAKMT2AMAOBSMN1; SMN2MAOA
SCHEMBL7248605 0.73 GAA (0.74) GAAKMT2AMAOBSMN1; SMN2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed