SCHEMBL9375800

SCHEMBL9375800

CC(C)(C)c1cc(CCC(=O)NN2C(=O)c3ccc4cc3C(=O)N(NC(=O)CCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(=O)c3cc-4ccc3C2=O)cc(C(C)(C)C)c1O

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.54
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.45
MAOB P27338 3/20 0.44
MAOA P21397 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
AGTR1 P30556 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43
ACHE P22303 1/20 0.42
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
GSK3B P49841 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9379388 0.95 GAA (0.52) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9375891 0.85 GAA (0.48) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9743605 0.80 GAA (0.62) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9545502 0.79 GAA (0.60) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9376633 0.78 GAA (0.41) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9373786 0.75 GAA (0.55) GAAKMT2AMEN1MAOBMAOA
SCHEMBL2741339 0.74 GAA (0.60) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9376680 0.74 GAA (0.60) GAAKMT2AMEN1MAOBMAOA
SCHEMBL39122 0.74 GAA (0.77) GAAKMT2AMEN1MAOBMAOA
SCHEMBL13199504 0.73 GAA (0.59) GAAKMT2AMEN1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP claimed
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed