SCHEMBL9374136

SCHEMBL9374136

CC(=O)N1CCC(=C2c3ccc(Cl)cc3SCc3cccnc32)CC1=O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.61
FNTB P49356 10/20 0.61
SLC6A15 Q9H2J7 6/20 0.55
HRH1 P35367 5/20 0.55
PTAFR P25105 4/20 0.55
MGLL Q99685 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9374487 0.86 PTAFR (0.73) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL6996008 0.82 FNTA (0.71) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL9374145 0.81 FNTA (0.62) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL9734604 0.80 FNTA (0.58) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL9380583 0.79 FNTA (0.53) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL7000792 0.79 SLC6A15 (0.75) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL9563106 0.78 FNTA (0.78) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL6991647 0.76 FNTA (1.00) FNTAFNTBSLC6A15
SCHEMBL6993193 0.76 FNTA (0.79) FNTAFNTBSLC6A15HRH1PTAFR
SCHEMBL7003550 0.75 FNTA (1.00) FNTAFNTBSLC6A15HRH1PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0341860-B1 Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use SCHERING CORP (US) 1994-07-13 EP disclosed
US-5104876-A Antiallergens, antiinflammatory agent SCHERING CORPORATION 1992-04-14 US disclosed
EP-0341860-A1 Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use SCHERING CORPORATION (US) 1989-11-15 EP disclosed