Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.58 |
| ▸ | FNTB | P49356 | 9/20 | 0.58 |
| ▸ | SLC6A15 | Q9H2J7 | 8/20 | 0.52 |
| ▸ | HRH1 | P35367 | 6/20 | 0.52 |
| ▸ | PTAFR | P25105 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993665 | 0.90 | FNTA (0.56) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9374487 | 0.84 | PTAFR (0.73) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9374136 | 0.80 | FNTA (0.61) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6996008 | 0.80 | FNTA (0.71) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9374145 | 0.79 | FNTA (0.62) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL7000792 | 0.77 | SLC6A15 (0.75) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9563106 | 0.76 | FNTA (0.78) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6995016 | 0.76 | FNTA (0.52) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6989397 | 0.76 | FNTA (0.79) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL6993008 | 0.74 | HRH1 (0.49) | FNTAFNTBSLC6A15HRH1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104876-A | Antiallergens, antiinflammatory agent | SCHERING CORPORATION | 1992-04-14 | — | — | US | disclosed |
| EP-0341860-A1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |