SCHEMBL937480

SCHEMBL937480

COC(=O)C(N)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8814797 1.00
SCHEMBL61052 1.00
Hydrochloric Acid SCHEMBL28348104 0.98 LTA4H (0.37)
Hydrochloric Acid SCHEMBL938410 0.98 LTA4H (0.37)
Hydrochloric Acid SCHEMBL11344095 0.98 LTA4H (0.37)
SCHEMBL11776470 0.87 SMN1; SMN2 (0.42)
SCHEMBL24075464 0.86 CA1 (0.39)
SCHEMBL12534327 0.86 CA1 (0.39)
SCHEMBL930523 0.85 ZDHHC7 (0.40)
SCHEMBL930524 0.85 ZDHHC7 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1186332-C Novel thyroid receptor ligands and method II KAROBIO AB (SE) 2005-01-26 CN claimed
CN-1337953-A Novel thyroid receptor ligands and method II KAROBIO AB (SE) 2002-02-27 CN claimed
US-20250382380-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-12-18 US disclosed
US-20250353908-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-11-20 US disclosed
US-20250320271-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-10-16 US disclosed
EP-4626912-A2 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF Arcellx, Inc. (US) 2025-10-08 EP disclosed
US-12421291-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2025-09-23 US disclosed
EP-4600353-A2 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF Arcellx, Inc. (US) 2025-08-13 EP disclosed
EP-3710067-B1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX INC (US) 2025-07-02 EP disclosed
US-12338294-B2 D-domain containing polypeptides and uses thereof ARCELLX, INC. (US) 2025-06-24 US disclosed
US-20250154224-A1 D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF ARCELLX, INC. 2025-05-15 US disclosed
WO-2006022935-A1 SOLUBLE AMIDE &amp; ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS PARION SCIENCES, INC. (US) 2006-03-02 WO disclosed
US-20060040954-A1 Soluble amide &amp; ester pyrazinoylguanidine sodium channel blockers PARION SCIENCES, INC. (US) 2006-02-23 US disclosed
EP-1599096-A2 HETERO SUBSTITUED SODIUM CHANNEL BLOCKERS Parion Sciences, Inc. (US) 2005-11-30 EP disclosed
CN-1186332-C Novel thyroid receptor ligands and method II KAROBIO AB (SE) 2005-01-26 CN disclosed
WO-2004073629-A2 HETERO SUBSTITUED SODIUM CHANNEL BLOCKERS PARION SCIENCES, INC. (US) 2004-09-02 WO disclosed
CN-1401621-A Intermediate for preparing tricyclic compound and preparation method of intermediate HOECHST MARION ROUSSEL INC (FR) 2003-03-12 CN disclosed
CN-1090178-C Tricyclic compounds having activity specific for integrins, in particular alpha v beta 3 integrins, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them HOECHST MARION ROUSSEL INC (FR) 2002-09-04 CN disclosed
CN-1337953-A Novel thyroid receptor ligands and method II KAROBIO AB (SE) 2002-02-27 CN disclosed
CN-1219165-A Tricyclic compounds having activity specific for integrins, in particular alpha v beta 3 integrins, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them HOECHST MARION ROUSSEL CO (FR) 1999-06-09 CN disclosed