Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 6/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.60 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377503 | 0.82 | RAB9A (0.78) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL9381341 | 0.80 | RAB9A (0.55) | PIK3CARAB9ANPC1SMN1; SMN2PIK3CG | |
| SCHEMBL9376809 | 0.77 | PI4KA (0.56) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL9382376 | 0.76 | RAB9A (0.55) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| Hydrochloric Acid SCHEMBL7331641 | 0.76 | RAB9A (0.66) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL113955 | 0.76 | RAB9A (0.76) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL9722768 | 0.76 | RAB9A (0.66) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL3710444 | 0.75 | PIK3CA (1.00) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL13780339 | 0.75 | RAB9A (0.81) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C | |
| SCHEMBL9376258 | 0.75 | RAB9A (0.56) | PI4KAPI4KBPIK3CDPIK3CAPIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |