Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TPI1 | P60174 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosamine SCHEMBL163122 | 1.00 | TSHR (0.42) | TSHRPPARDALOX15TP53TDP1 | |
| Fosamine SCHEMBL8535758 | 0.98 | TSHR (0.43) | TSHRPPARDALOX15TP53TDP1 | |
| Fosamine SCHEMBL64451 | 0.98 | — | — | |
| Fosamine SCHEMBL11740060 | 0.89 | PPARD (0.38) | TSHRPPARDALOX15TP53TDP1 | |
| Fosamine SCHEMBL11742074 | 0.87 | SAT1 (0.37) | TSHRPPARDALOX15TP53TDP1 | |
| Fosamine SCHEMBL11882271 | 0.86 | PPARD (0.35) | TSHRPPARDALOX15TP53TDP1 | |
| Fosamine SCHEMBL11742086 | 0.85 | CA12 (0.40) | TSHRPPARDCA12CA1CA2 | |
| Fosamine SCHEMBL11742068 | 0.84 | CA12 (0.32) | TSHRPPARDCA12CA1CA2 | |
| Fosamine SCHEMBL11740910 | 0.78 | MEN1 (0.34) | TSHRPPARD | |
| Glyphosate SCHEMBL9271349 | 0.77 | EGLN1 (0.31) | PPARDCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586568-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |