Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869232 | 1.00 | TSHR (0.52) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL22869234 | 1.00 | TSHR (0.52) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL19365113 | 0.90 | TSHR (0.48) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL7921047 | 0.86 | TSHR (0.55) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL14765414 | 0.86 | TSHR (0.55) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL24601306 | 0.83 | TSHR (0.43) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL13296959 | 0.81 | TSHR (0.46) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL24313653 | 0.81 | TSHR (0.42) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL17831609 | 0.81 | TSHR (0.42) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL25979999 | 0.81 | TSHR (0.42) | TSHRCHRM2CHRM1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56039090-A | — | — | None | — | — | JP | disclosed |
| EP-0318894-B1 | Titanocenes, their use and N-substituted pyrroles | CIBA GEIGY AG (CH) | 1994-02-16 | — | — | EP | disclosed |
| US-5106722-A | Photoiniators having cyclopentadieneyl or indenyl groups and fluorinated aryl or heterocyclic ring; photoresists of unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-5008302-A | Photoinitiators for radiation-induced polymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0318894-A2 | Titanocenes, their use and N-substituted pyrroles | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| JP-S5639090-A | 5-SUBSTITUTED URACIL DERIVATIVE AND ITS PREPARATION | TAIHO YAKUHIN KOGYO KK | 1981-04-14 | — | — | JP | disclosed |
| US-4176190-A | Diuretic and saliuretic sulphamoylbenzoic acids | CIBA-GEIGY CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |
| US-4016283-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3984436-A | BLOCKERS OF ADRENERGIC B-RECEPTORS | CIBA-GEIGY CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |