Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765414 | 1.00 | TSHR (0.55) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL22869234 | 0.86 | TSHR (0.52) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL22869232 | 0.86 | TSHR (0.52) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL9375474 | 0.86 | TSHR (0.52) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL17818351 | 0.80 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL13296959 | 0.78 | TSHR (0.46) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL19365113 | 0.77 | TSHR (0.48) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL24601306 | 0.75 | TSHR (0.43) | TSHRCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL8718540 | 0.74 | TSHR (0.65) | TSHRCA9CA12CA1CA2 | |
| SCHEMBL17831609 | 0.74 | TSHR (0.42) | TSHRCHRM2CHRM1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085377-A2 | HYDROXAMIC ACID DERIVATIVES | CRYSTAL BIOPHARMACEUTICAL LLC (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20070015260-A1 | Synthesis of synthons for the manufacture of bioactive compounds | DIVERSA CORPORATION | 2007-01-18 | — | — | US | disclosed |