Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 16/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567448 | 0.84 | CA2 (0.52) | CA2FFAR1DRD2 | |
| SCHEMBL1044755 | 0.84 | CA2 (0.53) | CA2CA1FFAR1CYP2C9CYP2B6 | |
| SCHEMBL6980879 | 0.84 | CA2 (0.53) | CA2CA1FFAR1CYP2C9CYP2B6 | |
| SCHEMBL6740016 | 0.82 | FFAR1 (0.51) | CA2FFAR1CYP2C9CYP2B6SLCO1B3 | |
| SCHEMBL7982000 | 0.82 | CA2 (0.55) | CA2 | |
| SCHEMBL2544576 | 0.82 | CA2 (0.55) | CA2 | |
| SCHEMBL1545420 | 0.82 | CA2 (0.55) | CA2 | |
| SCHEMBL17272699 | 0.82 | CA2 (0.53) | CA2CA1FFAR1CYP2C9CYP2B6 | |
| SCHEMBL17272700 | 0.82 | CA2 (0.53) | CA2CA1FFAR1CYP2C9CYP2B6 | |
| SCHEMBL12056274 | 0.82 | CA2 (0.65) | CA2CA1FFAR1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445026-B1 | Aminomethylpiperidine derivatives, their process for preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1994-01-26 | — | — | EP | disclosed |
| US-5229399-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-07-20 | — | — | US | disclosed |
| US-5229398-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-07-20 | — | — | US | disclosed |
| US-5192775-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-03-09 | — | — | US | disclosed |
| EP-0445026-A1 | Aminomethylpiperidine derivatives, their process for preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-04 | — | — | EP | disclosed |