Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9376788 | 0.99 | PIK3CG (0.34) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9377336 | 0.91 | PIK3CG (0.36) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9380282 | 0.91 | PIK3CG (0.36) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9375319 | 0.90 | PIK3CG (0.38) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9376779 | 0.88 | LCK (0.36) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9380562 | 0.88 | NPC1 (0.39) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9378810 | 0.88 | PIK3CG (0.37) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9376672 | 0.88 | PIK3CG (0.34) | PIK3CGLCKNPC1USP2RAB9A | |
| Hydrochloric Acid SCHEMBL9376404 | 0.87 | NPC1 (0.38) | PIK3CGLCKNPC1USP2RAB9A | |
| SCHEMBL9377610 | 0.85 | LCK (0.38) | PIK3CGLCKNPC1RAB9APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |