Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9376404 | 0.99 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9378810 | 0.91 | PIK3CG (0.37) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9377336 | 0.89 | PIK3CG (0.36) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9376779 | 0.89 | LCK (0.36) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9377550 | 0.89 | PIK3CG (0.41) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9380282 | 0.89 | PIK3CG (0.36) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9378049 | 0.89 | MAPT (0.38) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9375795 | 0.88 | PIK3CG (0.35) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9381311 | 0.88 | SMN1; SMN2 (0.37) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL9375319 | 0.88 | PIK3CG (0.38) | NPC1RAB9ASMN1; SMN2USP2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |