Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269251 | 0.89 | DHFR (0.45) | DHFRCYP1A2CYP2A6TAAR1NOS3 | |
| SCHEMBL22460731 | 0.85 | DHFR (0.43) | DHFRCYP1A2CYP2A6TAAR1NOS3 | |
| SCHEMBL18682734 | 0.82 | CCR1 (0.52) | CYP2A6NOS3NOS2MEN1RAB9A | |
| SCHEMBL20909966 | 0.79 | MCHR1 (0.53) | DHFRMAOBTAAR1RAB9AACHE | |
| SCHEMBL657443 | 0.79 | HRH1 (0.47) | CYP1A2CYP2A6TAAR1NOS3NOS2 | |
| SCHEMBL19200847 | 0.79 | PDE10A (0.43) | DHFRCYP1A2NOS3NOS2NPC1 | |
| SCHEMBL18648928 | 0.79 | TSHR (0.43) | CYP1A2NOS3NOS2MEN1KMT2A | |
| SCHEMBL10504713 | 0.78 | SMN1; SMN2 (0.52) | NOS3NOS2MEN1NPC1RAB9A | |
| SCHEMBL29160674 | 0.78 | TAAR1 (0.44) | MAOBTAAR1ACHEPDE10AHTR2A | |
| SCHEMBL19255610 | 0.78 | GFER (0.74) | GFERMAOAMAOBCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |