Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370592 | 0.74 | CHRM2 (0.46) | CHRM2EPHX2HSD11B1 | |
| SCHEMBL9369060 | 0.74 | CHRM2 (0.55) | CHRM2 | |
| SCHEMBL9369050 | 0.74 | CHRM2 (0.54) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9372763 | 0.73 | CHRM2 (0.54) | CHRM2 | |
| SCHEMBL9369947 | 0.72 | CHRM2 (0.52) | CHRM2 | |
| SCHEMBL9369870 | 0.72 | CHRM2 (0.55) | CHRM2 | |
| SCHEMBL9369613 | 0.72 | CHRM2 (0.49) | CHRM2 | |
| SCHEMBL9372338 | 0.71 | CHRM2 (0.54) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9372376 | 0.71 | CHRM2 (0.54) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9369958 | 0.68 | CHRM2 (0.58) | CHRM2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0307140-A1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |