Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370327 | 0.78 | HTR2C (0.43) | EPHX2HTR2C | |
| SCHEMBL8660094 | 0.76 | EPHX2 (0.55) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL9070490 | 0.75 | EPHX2 (0.51) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL3334093 | 0.75 | EPHX2 (0.51) | EPHX2HTR2CPLD1HTR3EHTR3B | |
| Water SCHEMBL8415043 | 0.74 | EPHX2 (0.50) | EPHX2HTR2CPLD1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL8703350 | 0.74 | EPHX2 (0.50) | EPHX2HTR2CKDM4EALDH1A1HTR3E | |
| SCHEMBL15533598 | 0.74 | EPHX2 (0.52) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| SCHEMBL615931 | 0.73 | EPHX2 (0.59) | EPHX2HTR2CPLD1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9076651 | 0.73 | PARP1 (0.49) | EPHX2HTR2CKDM4EALDH1A1HTR3E | |
| Hydrochloric Acid SCHEMBL23124285 | 0.72 | EPHX2 (0.58) | EPHX2HTR2CPLD1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594702-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS. | UPJOHN CO (US) | 1994-05-04 | — | — | EP | disclosed |
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |