Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376484 | 0.78 | EPHX2 (0.50) | HTR2CEPHX2 | |
| SCHEMBL13116668 | 0.75 | HTR2C (0.56) | HTR2CEPHX2 | |
| SCHEMBL18484592 | 0.73 | HTR2C (0.45) | HTR2CEPHX2 | |
| SCHEMBL13116676 | 0.71 | HRH4 (0.44) | HTR2CEPHX2 | |
| SCHEMBL23561114 | 0.71 | HTR2C (0.49) | HTR2CEPHX2 | |
| SCHEMBL9688903 | 0.69 | HTR2C (0.42) | HTR2CEPHX2 | |
| SCHEMBL122262 | 0.69 | USP2 (0.55) | HTR2CEPHX2 | |
| SCHEMBL9690012 | 0.68 | ADRB2 (0.40) | HTR2C | |
| SCHEMBL27538607 | 0.68 | HRH4 (0.42) | HTR2C | |
| SCHEMBL121912 | 0.67 | HTR2C (0.49) | HTR2CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594702-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS. | UPJOHN CO (US) | 1994-05-04 | — | — | EP | disclosed |