Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 7/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922430 | 0.90 | PRKD1 (0.52) | PRKD1ADRB1ADRB3ADRB2PPARG | |
| SCHEMBL936381 | 0.85 | PRKD1 (0.77) | PRKD1PPARGPPARAPRKD3PRKD2 | |
| SCHEMBL936379 | 0.85 | PRKD1 (0.77) | PRKD1PPARGPPARAPRKD3PRKD2 | |
| SCHEMBL12171379 | 0.84 | MAPT (0.53) | PRKD1PPARGPPARANPC1CASP3 | |
| SCHEMBL12171540 | 0.81 | ABCB1 (0.51) | PRKD1PPARGPPARANPC1CASP3 | |
| SCHEMBL5206252 | 0.79 | NPC1 (0.66) | PPARGPPARANPC1CASP3RAB9A | |
| SCHEMBL966138 | 0.78 | PRKD1 (0.62) | PRKD1PPARGPPARAPRKD3PRKD2 | |
| SCHEMBL4876695 | 0.78 | NPC1 (0.68) | PPARGPPARANPC1CASP3RAB9A | |
| SCHEMBL960012 | 0.77 | NPC1 (0.52) | PRKD1PPARGPPARANPC1CASP3 | |
| SCHEMBL957155 | 0.76 | PTPN1 (0.61) | PPARGPPARANPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |