Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073386 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL2608307 | 0.80 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL11743247 | 0.80 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL21527117 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL862550 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL24181416 | 0.76 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9ACYP2A6ALDH1A1 | |
| SCHEMBL2161965 | 0.76 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL2263518 | 0.76 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL2161969 | 0.76 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B | |
| SCHEMBL11959565 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246795-B | Isoxazoline compound containing ether structure at 4-phenyl para-position, preparation method thereof and application thereof as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-115246795-A | Isoxazoline compound with 4-phenyl para-position containing ether structure, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| EP-0399645-B1 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1994-11-09 | — | — | EP | disclosed |
| EP-0399645-A2 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4581365-A | Trichloroacryloyl oxime fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | disclosed |