Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | FGF23 | Q9GZV9 | 4/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762978 | 1.00 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL2161965 | 1.00 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL28407082 | 0.97 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL10733330 | 0.87 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL4275687 | 0.86 | KMT2A (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL5668373 | 0.86 | KMT2A (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL4275683 | 0.86 | KMT2A (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL11743247 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL2608307 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL91114 | 0.76 | ALDH1A1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118718469-A | Safe and efficient extracting agent for removing phenol and oil and application thereof | 中国科学院过程工程研究所 | 2024-10-01 | — | — | CN | claimed |
| CN-118184675-A | Mugwort lactone I derivative and pharmaceutical composition thereof, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-114835660-B | Preparation method of oxime ether | 浙江理工大学 | 2024-03-22 | — | — | CN | claimed |
| CN-114835660-A | Preparation method of oxime ether | 浙江理工大学 | 2022-08-02 | — | — | CN | claimed |
| CN-102367230-B | Method for synthesizing nitrile from aldoxime | UNIV YANGZHOU | 2013-09-18 | — | — | CN | claimed |
| EP-1527165-A4 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | DU PONT (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1527165-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. du Pont de Nemours and Company (US) | 2005-05-04 | — | — | EP | claimed |
| US-20030215929-A1 | Rhodococcus gene encoding aldoxime dehydratase | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-20 | — | — | US | claimed |
| WO-2003078581-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-25 | — | — | WO | claimed |
| CN-119930463-A | Asymmetric catalytic synthesis method of oxime ether compound with high optical purity | 南方科技大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119841718-A | Method for removing oxime from aldoxime | 扬州大学 | 2025-04-18 | — | — | CN | disclosed |
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-04-03 | — | — | US | disclosed |
| EP-4522608-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2025-03-19 | — | — | EP | disclosed |
| CN-118718469-A | Safe and efficient extracting agent for removing phenol and oil and application thereof | 中国科学院过程工程研究所 | 2024-10-01 | — | — | CN | disclosed |
| US-4283403-A | Substituted isoxazolines for control of plant phytopathogens | ELI LILLY AND COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0014232-A1 | Polyphosphazene polymers containing substituents derived from ketoximes and process for producing them | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| US-4018645-A | Method of controlling slime during paper manufacture using alpha-chloro-acylbenzaldoxime derivatives | SOMAR MANUFACTURING CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |
| US-3983246-A | N-(sulfonyloxy) benzimidoyl halides as bactericidal or fungicidal agents | FMC CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3968240-A | α-Chloro-o-acylbenzaldoxime derivatives as slime control agents | SOMAR MANUFACTURING CO., LTD. (JA) | 1976-07-06 | — | — | US | disclosed |
| US-3948861-A | Polyamide-imides from bis-imide and dialdoxime | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | NOS2, NOS1, NOS3 | NPC1 4600/4885RAB9A 4013/4885SMN1; SMN2 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.