Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046693 | 0.88 | TBXAS1 (0.56) | TBXA2RTBXAS1 | |
| SCHEMBL9372251 | 0.85 | TBXA2R (0.40) | TBXA2RTBXAS1 | |
| SCHEMBL9371887 | 0.83 | TBXA2R (0.58) | TBXA2RTBXAS1 | |
| SCHEMBL9371319 | 0.83 | TBXA2R (0.71) | TBXA2RTBXAS1 | |
| SCHEMBL9371517 | 0.83 | TBXAS1 (0.71) | TBXA2RTBXAS1 | |
| SCHEMBL7513748 | 0.82 | MAPT (0.43) | TBXA2RTBXAS1 | |
| SCHEMBL10562607 | 0.82 | MAPT (0.43) | TBXA2RTBXAS1 | |
| SCHEMBL4009695 | 0.82 | MAPT (0.43) | TBXA2RTBXAS1 | |
| SCHEMBL9375459 | 0.81 | TBXA2R (0.73) | TBXA2RTBXAS1 | |
| SCHEMBL10564573 | 0.81 | HPGD (0.42) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312051-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5010087-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-5010104-A | Antiischemic agent, cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0312051-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |