Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 16/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.53 |
| ▸ | MITF | O75030 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 14/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 10/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763242 | 0.89 | HTT (0.55) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL9372838 | 0.85 | HTT (0.38) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL2361037 | 0.83 | HTT (0.54) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL14574536 | 0.82 | HTT (0.56) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL15674046 | 0.82 | HTT (0.58) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL10360715 | 0.80 | HTT (0.54) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL10884770 | 0.79 | HTT (0.53) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL9234092 | 0.79 | HTT (0.57) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL10876189 | 0.78 | HTT (0.55) | HTTALDH1A1MITFNPC1SMN1; SMN2 | |
| SCHEMBL9194366 | 0.78 | HTT (0.55) | HTTALDH1A1MITFNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302346-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| EP-0201765-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4945091-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| US-4892947-A | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0302346-A2 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |