Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 13/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | MITF | O75030 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234092 | 0.89 | HTT (0.57) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL27691970 | 0.85 | HTT (0.42) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL10824672 | 0.83 | KMT2A (0.41) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL2323909 | 0.83 | GAA (0.41) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL9377271 | 0.83 | HTT (0.53) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL14574536 | 0.82 | HTT (0.56) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL980058 | 0.82 | HTT (0.60) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL10360715 | 0.80 | HTT (0.54) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL13788479 | 0.80 | ALDH1A1 (0.49) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL9763254 | 0.79 | HTT (0.50) | HTTALDH1A1SMN1; SMN2RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1180882-A | — | — | None | — | — | JP | disclosed |
| JP-11310574-A | — | — | None | — | — | JP | disclosed |
| US-20250242063-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-07-31 | — | — | US | disclosed |
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-3323810-A2 | AUTOMATED REACTION SYSTEM, CASSETTE AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| EP-2534136-B1 | METHODS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9603951-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| WO-2011097649-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| JP-H11310574-A | NITROPYRIDAZINONE COMPOUND AND ITS PRODUCTION | NISSAN CHEM IND LTD | 1999-11-09 | — | — | JP | disclosed |
| US-5026850-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0391390-A1 | Pyridazinones having insecticidal and acaricidal activity and compositions containing them | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1990-10-10 | — | — | EP | disclosed |
| JP-H01180882-A | PYRIDAZINONE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDAL AND ACARICIDAL AGENT CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1989-07-18 | — | — | JP | disclosed |
| US-4532239-A | N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0054946-B1 | BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054946-A1 | Basic substituted pyridazines, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
| US-20250242063-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | HTT 4436/4885ALDH1A1 1208/4885SMN1; SMN2 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.