Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395491 | 0.83 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL29614829 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL29966674 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL29942654 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL3076524 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL4512439 | 0.80 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL31061155 | 0.78 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL18806858 | 0.77 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL4954320 | 0.74 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2BCHEKDM4E | |
| SCHEMBL29371290 | 0.72 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2BCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338346-B1 | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4933342-A | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0338346-A2 | Quinoxaline derivatives and antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-25 | — | — | EP | disclosed |