Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081348 | 1.00 | HTR2C (0.47) | HTR2CHTR2AHTR2BSLC5A2CES2 | |
| SCHEMBL1594507 | 0.81 | HTR2C (0.41) | HTR2CSLC5A2 | |
| SCHEMBL12056442 | 0.81 | HTR2C (0.41) | HTR2CSLC5A2 | |
| SCHEMBL9380359 | 0.81 | HTR2C (0.41) | HTR2CSLC5A2 | |
| SCHEMBL30450943 | 0.80 | MAPT (0.42) | HTR2CHTR2AHTR2BSLC5A2HTR1A | |
| SCHEMBL4087278 | 0.77 | SLC5A2 (0.50) | HTR2CHTR2AHTR2BSLC5A2 | |
| SCHEMBL4717027 | 0.77 | SLC5A2 (0.50) | HTR2CHTR2AHTR2BSLC5A2 | |
| SCHEMBL4987870 | 0.77 | SLC5A2 (0.50) | HTR2CHTR2AHTR2BSLC5A2 | |
| SCHEMBL4986893 | 0.77 | SLC5A2 (0.50) | HTR2CHTR2AHTR2BSLC5A2 | |
| SCHEMBL4077149 | 0.76 | SLC5A2 (0.46) | SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |