Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056442 | 1.00 | HTR2C (0.41) | HTR2CSLC5A2ALDH1A1TSHRMEN1 | |
| SCHEMBL1594507 | 1.00 | HTR2C (0.41) | HTR2CSLC5A2ALDH1A1TSHRMEN1 | |
| SCHEMBL10779413 | 0.81 | SLC5A2 (0.43) | SLC5A2ALDH1A1TSHRMAPT | |
| SCHEMBL29102158 | 0.81 | ESR1 (0.39) | SLC5A2ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL4081348 | 0.81 | HTR2C (0.47) | HTR2CSLC5A2 | |
| SCHEMBL9377705 | 0.81 | HTR2C (0.47) | HTR2CSLC5A2 | |
| SCHEMBL19329994 | 0.79 | EPHX1 (0.43) | SLC5A2ALDH1A1MEN1GAAMAPT | |
| SCHEMBL4077235 | 0.79 | EPHX1 (0.43) | SLC5A2ALDH1A1MEN1GAAMAPT | |
| SCHEMBL4086552 | 0.79 | EPHX1 (0.43) | SLC5A2ALDH1A1MEN1GAAMAPT | |
| SCHEMBL4086313 | 0.77 | SLC5A2 (0.40) | SLC5A2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |