Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374927 | 0.88 | MAPK14 (0.40) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL18672225 | 0.83 | HTT (0.37) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL18672242 | 0.82 | NR2E3 (0.35) | ALDH1A1SMN1; SMN2HTTMAPTMAPK14 | |
| SCHEMBL19313567 | 0.81 | HTT (0.39) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL20170593 | 0.80 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HTTMAPK14 | |
| SCHEMBL18672227 | 0.79 | MAPK14 (0.38) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL19313466 | 0.79 | NR2E3 (0.40) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL18672244 | 0.79 | HTT (0.37) | ALDH1A1SMN1; SMN2HTTMAPTMITF | |
| SCHEMBL19356577 | 0.78 | MAPK14 (0.38) | ALDH1A1SMN1; SMN2HTTMAPK14 | |
| SCHEMBL18401357 | 0.78 | MAPK14 (0.36) | ALDH1A1SMN1; SMN2HTTMITFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302346-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4945091-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| EP-0302346-A2 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |