SCHEMBL937818

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL937005	0.86	RAF1 (0.60)	KDRRAF1BRAFABL1RET
	SCHEMBL937919	0.85	ALDH1A1 (0.38)	KDRRAF1BRAFMAPK14MAPK13
	SCHEMBL937748	0.79	RAF1 (0.37)	RAF1BRAFMAPK14MAPK13LYN
	SCHEMBL938508	0.75	RET (0.69)	KDRRAF1BRAFABL1RET
	SCHEMBL939153	0.75	RAF1 (0.63)	KDRRAF1BRAFABL1RET
	SCHEMBL5426692	0.73	KDR (0.51)	KDRRAF1BRAFABL1MAPK14
	SCHEMBL3542762	0.72	RAF1 (0.58)	KDRRAF1BRAFABL1RET
	SCHEMBL3475376	0.72	RAF1 (0.64)	KDRRAF1ABL1RETMAPK14
	SCHEMBL939889	0.71	RAF1 (0.61)	KDRRAF1BRAFMAPK14MAPK13
	SCHEMBL937135	0.71	RAF1 (0.37)	RAF1BRAFMAPK14MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.