SCHEMBL937883

SCHEMBL937883

CCCCCCCCCCCCCOC(OCCCCCCCCCCCC)C(O)COc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.40
PLA2G4B P0C869 1/20 0.39
PLK1 P53350 3/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PTPN11 Q06124 2/20 0.36
NR5A1 Q13285 1/20 0.36
CNR1 P21554 3/20 0.34
ENPP2 Q13822 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3700899 1.00 CNR2 (0.40) CNR2PLA2G4BPLK1CYP3A4CYP2C9
SCHEMBL4562628 0.88 PLK1 (0.36) CNR2PLA2G4BPLK1CYP3A4CYP2C9
SCHEMBL1552126 0.87 CNR2 (0.34) CNR2PLA2G4BPLK1CYP3A4CYP2C9
SCHEMBL1552093 0.87 CNR2 (0.34) CNR2PLA2G4BPLK1CYP3A4CYP2C9
SCHEMBL537022 0.87 CNR2 (0.34) CNR2PLA2G4BPLK1CYP3A4CYP2C9
SCHEMBL45412 0.86 NR5A1 (0.49) CNR2PLK1PTPN11NR5A1TP53
SCHEMBL38944 0.86 NR5A1 (0.49) CNR2PLK1PTPN11NR5A1TP53
SCHEMBL78927 0.86 NR5A1 (0.49) CNR2PLK1PTPN11NR5A1TP53
SCHEMBL22216823 0.86 NR5A1 (0.49) CNR2PLK1PTPN11NR5A1TP53
SCHEMBL1309485 0.86 NR5A1 (0.49) CNR2PLK1PTPN11NR5A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947540-B1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM FRAUNHOFER GES FORSCHUNG (DE) 2023-08-16 EP disclosed
US-20110015315-A1 PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES FREY MARKUS 2011-01-20 US disclosed
US-6593403-B1 Additive mixture for improving the mechanical properties of polymers CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015315-A1 PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES PNMT, PAH, PAOX CNR2 1066/4885PLA2G4B 3940/4885PLK1 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.