Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 6/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377521 | 0.94 | KCNH2 (0.63) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9666823 | 0.93 | KCNH2 (0.69) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9376728 | 0.92 | ALDH1A1 (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL8890201 | 0.90 | KCNH2 (0.71) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9381301 | 0.89 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9377634 | 0.89 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9179692 | 0.89 | KCNH2 (0.66) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9378560 | 0.88 | KCNH2 (0.50) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL9177705 | 0.88 | KCNH2 (0.65) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10719094 | 0.88 | KCNH2 (0.59) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255908-B1 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER LAMBERT CO (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |
| US-4771055-A | BACTERICIDES | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0255908-A2 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER-LAMBERT COMPANY (US) | 1988-02-17 | — | — | EP | disclosed |