Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503489 | 0.92 | MAPT (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL1424370 | 0.80 | PARP1 (0.55) | PARP1 | |
| SCHEMBL29040046 | 0.80 | PARP1 (0.62) | MAPTKDM4ESMN1; SMN2TP53G6PD | |
| SCHEMBL29040009 | 0.80 | PARP1 (0.62) | MAPTKDM4ESMN1; SMN2TP53G6PD | |
| SCHEMBL29769683 | 0.79 | PARP1 (0.59) | KDM4EHSD17B10PARP1 | |
| SCHEMBL15722032 | 0.79 | PARP1 (0.59) | KDM4EHSD17B10PARP1 | |
| SCHEMBL19475394 | 0.79 | POLB (0.44) | KDM4EPARP1PARP2 | |
| SCHEMBL24415021 | 0.78 | PDE10A (0.40) | KDM4EPARP1PARP2LMNA | |
| SCHEMBL14644025 | 0.78 | LMNA (0.42) | ALDH1A1MAPTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10123198 | 0.78 | POLB (0.45) | KDM4EPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329073-B1 | 2-Substituted carbonylimidazo[4,5-c]quinolines | SHIONOGI & CO (JP) | 1994-12-28 | — | — | EP | disclosed |