Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378209 | 0.90 | SHMT2 (0.46) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9378235 | 0.88 | SHMT2 (0.42) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9379889 | 0.88 | KMT2A (0.49) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9379697 | 0.88 | SHMT2 (0.42) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9377633 | 0.88 | POLB (0.45) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9379615 | 0.86 | SHMT2 (0.49) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9382490 | 0.86 | SHMT2 (0.43) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9379666 | 0.86 | GAA (0.43) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9378519 | 0.85 | GAA (0.57) | SHMT2GAAALDH1A1L3MBTL1TAAR1 | |
| SCHEMBL9379677 | 0.85 | CD274 (0.52) | SHMT2TAAR1HTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |