Strychnine

Strychnine

SCHEMBL93798

O=C1C[C@@H]2OCC=C3CN4CC[C@]56c7ccccc7N1[C@H]5[C@H]2[C@H]3C[C@H]46

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 13/20 1.00
GLRB P48167 13/20 1.00
CYP3A4 P08684 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
TAS2R10 Q9NYW0 2/20 1.00
SCN1A P35498 1/20 1.00
TAS2R46 P59540 1/20 1.00
SCN2A Q99250 1/20 1.00
SCN3A Q9NY46 1/20 1.00
CHRM1 P11229 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
CHRM2 P08172 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Strychnine SCHEMBL14047653 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL21985190 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL29352583 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL29362678 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL12549549 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL14029424 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL14117483 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL25300604 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL31047368 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL184168 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14353 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-2991482-B1 PACKAGED RODENTICIDAL BAIT BASF AGRO BV (NL) 2026-05-20 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
CN-120064532-A Detection method and application of jade leaf detoxification granules 三金集团湖南三金制药有限责任公司 2025-05-30 CN claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
CN-116672353-B Traditional Chinese medicine composition for enhancing phagocytic capacity of macrophages and preparation method thereof 浙江大学智能创新药物研究院 2025-05-16 CN claimed
US-12279613-B2 Attractant blend compositions, devices and methods for attracting female mice VARNER ELANA (US) 2025-04-22 US claimed
CN-119345263-B A Chinese medicinal composition for treating rheumatoid diseases composition for treating osteoarthritis 津药达仁堂集团股份有限公司中药研究院 2025-04-18 CN claimed
US-4841668-A Gopher killer MCKENZIE CARL O (US) 1989-06-27 US claimed
WO-1989005301-A1 USE OF COMPOUNDS OF THE RETULINE SERIES AS COMPOUNDS WITH PHARMACEUTICAL ACTIVITY, IN PARTICULAR ANALGESIC, ANTISPASMODIC AND ANTIINFLAMMATORY MEDICAMENTS UNIVERSITE DE LIEGE (BE) 1989-06-15 WO claimed
EP-0273349-A2 Resolution of 1,4-dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1988-07-06 EP claimed
US-4746616-A DETECTION OF TAMPERING THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) 1988-05-24 US claimed
EP-0249245-A2 Antihypertensive dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1987-12-16 EP claimed
EP-0128684-A1 Process for producing 3-(3,4-dihydroxyphenyl) serine SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1984-12-19 EP claimed
EP-0117080-A2 Skin treatment composition UNILEVER PLC (GB) 1984-08-29 EP claimed
US-4224457-A Process for manufacturing optically active sulfur-containing carboxylic acid SANTEN PHARMACEUTICAL CO., LTD. (JP) 1980-09-23 US claimed
US-4048224-A Process for resolving alanine, 3-fluoro and 2-deutero-3-fluoro-DL-alanine MERCK & CO., INC. (US) 1977-09-13 US claimed
US-4042698-A Treatment of myasthenia gravis and oral medication therefor ZAPPIA JOSEPH FRANCIS 1977-08-16 US claimed