Strychnine

Strychnine

SCHEMBL14029424

O=C1C[C@@H]2OCC=C3CN4CC[C@]56c7ccccc7N1[C@H]5[C@H]2[C@H]3C[C@H]46

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 13/20 1.00
GLRB P48167 13/20 1.00
CYP3A4 P08684 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
TAS2R10 Q9NYW0 2/20 1.00
SCN1A P35498 1/20 1.00
TAS2R46 P59540 1/20 1.00
SCN2A Q99250 1/20 1.00
SCN3A Q9NY46 1/20 1.00
CHRM1 P11229 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
CHRM2 P08172 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Strychnine SCHEMBL93798 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL14047653 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL21985190 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL29352583 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL29362678 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL12549549 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL14117483 1.00 GLRA1 (1.00) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL25300604 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL31047368 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A
Strychnine SCHEMBL184168 0.99 GLRA1 (0.98) GLRA1GLRBCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2991482-B1 PACKAGED RODENTICIDAL BAIT BASF AGRO BV (NL) 2026-05-20 EP claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
EP-3847589-B1 COGNITIVE COMPUTING METHODS AND SYSTEMS BASED ON BIOLOGICAL NEURAL NETWORKS ALPVISION S A (CH) 2024-12-04 EP claimed
WO-2022036444-A1 ATTRACTANT BLEND COMPOSITION COMPRISING 2,3,5-TRITHIAHEXANE, 1-HEXANOL AND/OR 3-METHYL-2-PENTANONE, AND DEVICES AND METHODS FOR ATTRACTING FEMALE MICE GRIES GERHARD (CA) 2022-02-24 WO claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP disclosed
EP-4471790-B1 SYSTEM AND METHOD FOR DETERMINING MICROBIOME FROM HOST METABOLOME USING A MACHINE LEARNING MODEL MICROBIOTX HEALTH PRIVATE LTD (IN) 2026-04-01 EP disclosed
US-12576166-B2 Contrast agents for detection of enzyme activities based on melanin synthesis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-17 US disclosed
EP-3370539-B1 ADSORPTION SYSTEM AND METHOD FOR OPERATING AN ADSORPTION SYSTEM FLAVOLOGIC GMBH (DE) 2025-07-02 EP disclosed
US-12325646-B2 Fertigation water treatment UNIVERSITY OF GUELPH (CA) 2025-06-10 US disclosed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP disclosed
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2022-01-06 US disclosed
WO-2021210975-A1 CHROMIUM VI TEST MATINSPIRED B.V. (NL) 2021-10-21 WO disclosed
CN-106692113-A Strychnine percutaneous patch for treating hemiplegia and preparation method thereof 湘潭大学 2017-05-24 CN disclosed
US-20080267948-A1 Croos-B Structure Binding Compounds CROSSBETA BIOSCIENCES B.V. (NL) 2008-10-30 US disclosed
US-20080267948-A1 Croos-B Structure Binding Compounds CROSSBETA BIOSCIENCES B.V. (NL) 2008-10-30 US disclosed
CN-1102989-A Antiepilepsy medicine and preparing method TIEXI NEUROPSYCHOSIS HOSPITAL (CN) 1995-05-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080267948-A1 Croos-B Structure Binding Compounds CACYBP, TBCB, MYCBP GLRA1 2447/4885GLRB 121/4885CYP3A4 3998/4885
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH GLRA1 3716/4885GLRB 3732/4885CYP3A4 241/4885
US-12576166-B2 Contrast agents for detection of enzyme activities based on melanin synthesis TYR, MPO, LNPEP GLRA1 4825/4885GLRB 4710/4885CYP3A4 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.