Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728 | 0.87 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL13756 | 0.79 | BACE1 (0.71) | BACE1CTSD | |
| SCHEMBL17620371 | 0.75 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL9288 | 0.74 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL17620296 | 0.72 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL17620327 | 0.72 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL17620305 | 0.71 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL17620373 | 0.71 | BACE1 (0.76) | BACE1CTSD | |
| SCHEMBL17620334 | 0.71 | BACE1 (0.75) | BACE1CTSD | |
| SCHEMBL17620324 | 0.71 | BACE1 (0.78) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504315-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | Amgen Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011063233-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2011-05-26 | — | — | WO | disclosed |