Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383063 | 0.88 | MAPT (0.78) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL8790381 | 0.86 | MEN1 (1.00) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9383506 | 0.86 | MAPT (0.74) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9383200 | 0.86 | MAPT (0.74) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL2201836 | 0.85 | MAPT (0.64) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9379683 | 0.84 | KMT2A (0.70) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9382929 | 0.83 | MEN1 (0.84) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9378231 | 0.83 | MAPT (0.69) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9383446 | 0.83 | KMT2A (0.69) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL9382464 | 0.83 | KMT2A (0.65) | KMT2AMAPTMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269030-B1 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5089515-A | Antiischemic agents; pyrazolone compounds | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| US-4990619-A | Cardiovascular disorders, antiischemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4906644-A | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0269030-A2 | Lipid-peroxide formation inhibiting composition and novel compounds useful therefor | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-01 | — | — | EP | disclosed |