Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374739 | 0.88 | TSHR (0.54) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9379254 | 0.88 | KMT2A (0.54) | RAB9ANPC1MAPK14MEN1KMT2A | |
| SCHEMBL9378850 | 0.86 | KMT2A (0.50) | RAB9ANPC1MAPK14MEN1KMT2A | |
| SCHEMBL9379940 | 0.85 | KMT2A (0.58) | RAB9AMEN1KMT2AALDH1A1CA12 | |
| SCHEMBL9379514 | 0.84 | RAB9A (0.55) | RAB9ANPC1MAPK14MEN1PKM | |
| SCHEMBL9376028 | 0.84 | NPC1 (0.49) | RAB9ANPC1MAPK14MEN1KMT2A | |
| SCHEMBL9375312 | 0.84 | HDAC1 (0.50) | MAPK14PDK2PDK4 | |
| SCHEMBL9374793 | 0.84 | CYP26A1 (0.53) | MAPK14MEN1KMT2APDK2PDK4 | |
| SCHEMBL9378204 | 0.83 | KCNK3 (0.51) | RAB9ANPC1MAPK14MEN1KMT2A | |
| SCHEMBL9375391 | 0.83 | CYP26A1 (0.52) | RAB9ANPC1MAPK14MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |