Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 7/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 7/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 7/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9375280 | 0.82 | RAB9A (0.49) | RAB9ASMN1; SMN2TP53NPC1MET | |
| SCHEMBL9375773 | 0.78 | MAPT (0.34) | RAB9ASMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL9379336 | 0.75 | NPC1 (0.57) | LMNARAB9ASMN1; SMN2STAT1NPC1 | |
| SCHEMBL9379209 | 0.74 | POLB (0.48) | CASP3SENP8SENP7SENP6NPY1R | |
| SCHEMBL8019525 | 0.74 | NPC1 (0.59) | NPY1RPTPN1LMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9383081 | 0.73 | RAB9A (0.46) | RAB9ASMN1; SMN2TP53NPC1MET | |
| SCHEMBL9378049 | 0.73 | MAPT (0.38) | RAB9ASMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL9379322 | 0.72 | MAPT (0.44) | LMNARAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL9376418 | 0.72 | RAB9A (0.48) | RAB9ASMN1; SMN2TP53NPC1MET | |
| SCHEMBL8934510 | 0.72 | NPC1 (0.41) | RAB9ASMN1; SMN2TP53NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |