Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189370 | 1.00 | LMNA (0.54) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL9380317 | 1.00 | LMNA (0.54) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL30189346 | 0.84 | TSHR (0.49) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL4374324 | 0.82 | TDP1 (0.52) | TSHRALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL13707651 | 0.82 | TDP1 (0.52) | TSHRALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL28417090 | 0.82 | TSHR (0.46) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL9377209 | 0.82 | KDM4E (0.48) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL9377212 | 0.82 | KDM4E (0.48) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL29138542 | 0.81 | MAPT (0.50) | LMNATSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL22886586 | 0.79 | CDC25B (0.56) | TSHRALDH1A1HSD17B10MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438209-B1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5116404-A | URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0438209-A1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-07-24 | — | — | EP | disclosed |