Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059614 | 1.00 | F2 (0.40) | F2TMPRSS2HTR1AADRA2ACYP2D6 | |
| SCHEMBL9385821 | 0.75 | F2 (0.46) | F2TMPRSS2HTR1AADRA2ACYP2D6 | |
| SCHEMBL9059632 | 0.75 | F2 (0.46) | F2TMPRSS2HTR1AADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL9835312 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9836382 | 0.75 | — | — | |
| SCHEMBL12756975 | 0.74 | TDP1 (0.40) | — | |
| SCHEMBL9042983 | 0.70 | RAB9A (0.42) | MAOA | |
| SCHEMBL14155722 | 0.69 | CYP2D6 (0.42) | CYP2D6LMNATSHRPMP22HSD17B10 | |
| Hydrochloric Acid SCHEMBL9835123 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL9833802 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | claimed |