Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376244 | 0.84 | STING1 (0.62) | KDM4EMAOAALDH1A1HPGDMAPT | |
| SCHEMBL107952 | 0.81 | KDM4E (0.71) | KDM4EMAOAALDH1A1HPGDMAPT | |
| SCHEMBL29975151 | 0.81 | KDM4E (0.71) | KDM4EMAOAALDH1A1HPGDMAPT | |
| Trimethylammonium SCHEMBL27716678 | 0.79 | KDM4E (0.68) | KDM4EMAOAALDH1A1HPGDMAPT | |
| SCHEMBL4459419 | 0.76 | STING1 (0.75) | KDM4EMAOAALDH1A1HPGDMAPT | |
| SCHEMBL12835290 | 0.75 | CYP1A2 (0.59) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL9526692 | 0.74 | HSD17B10 (0.53) | KDM4EALDH1A1HPGDMAPTGLA | |
| SCHEMBL11320297 | 0.74 | KDM4E (0.56) | KDM4EMAOAALDH1A1HPGDMAPT | |
| SCHEMBL20744967 | 0.74 | STING1 (0.73) | KDM4EMAOASMN1; SMN2GLASTING1 | |
| SCHEMBL9381286 | 0.74 | STING1 (0.78) | KDM4EMAPTSMN1; SMN2GLASTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278176-B1 | Compounds having antitumour and antibacterial properties | WARNER LAMBERT CO (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5281620-A | Alkyl substituted xanthenone-4-acetic acid | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0278176-A2 | Compounds having antitumour and antibacterial properties | WARNER-LAMBERT COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |