Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380828 | 0.78 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9254867 | 0.70 | ALOX5 (0.54) | ALOX5PTGS2PTGS1 | |
| SCHEMBL9226945 | 0.70 | ALOX5 (0.38) | ALOX5PTGS2PTGS1 | |
| SCHEMBL9220235 | 0.67 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL9210632 | 0.67 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9222711 | 0.67 | ALOX5 (0.67) | ALOX5PTGS2PTGS1 | |
| SCHEMBL9380811 | 0.64 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL9253894 | 0.64 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL9385108 | 0.64 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL2785643 | 0.64 | CYP2A6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409413-B1 | Diaryl ether heterocycles | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |