Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268638 | 0.82 | KDM4E (0.56) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL9837091 | 0.81 | MEN1 (0.70) | TTRESR1ESR2MEN1KMT2A | |
| SCHEMBL7253352 | 0.80 | TTR (0.67) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL29838129 | 0.80 | TTR (0.67) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL9376949 | 0.79 | TTR (0.55) | TTRMEN1KMT2AKDM4EMAOA | |
| Xanthone SCHEMBL10615991 | 0.79 | TTR (0.65) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL9837415 | 0.76 | MEN1 (0.51) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL9836063 | 0.76 | KDM4E (0.49) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL16477282 | 0.75 | TTR (0.63) | TTRMEN1KMT2AKDM4EMAOA | |
| SCHEMBL20858465 | 0.74 | AHR (0.44) | MEN1KMT2AKDM4EMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278176-B1 | Compounds having antitumour and antibacterial properties | WARNER LAMBERT CO (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5281620-A | Alkyl substituted xanthenone-4-acetic acid | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0278176-A2 | Compounds having antitumour and antibacterial properties | WARNER-LAMBERT COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |