Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAOA | P21397 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837415 | 0.85 | MEN1 (0.51) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL9836158 | 0.84 | MEN1 (0.58) | MEN1KMT2AMAOAMAPTKDM4E | |
| SCHEMBL9380709 | 0.81 | TTR (0.49) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL9836063 | 0.81 | KDM4E (0.49) | MEN1KMT2AMAOATTRPTGS2 | |
| SCHEMBL14701609 | 0.79 | TTR (0.58) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL3268638 | 0.76 | KDM4E (0.56) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL9834774 | 0.76 | TTR (0.49) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL9835674 | 0.76 | PTGS2 (0.46) | MEN1KMT2AMAOAMAPTTTR | |
| SCHEMBL5312406 | 0.76 | KDM4E (0.68) | MEN1KMT2AMAOAMAPTKDM4E | |
| SCHEMBL24403683 | 0.75 | MAOA (0.61) | MEN1KMT2AMAOAMAPTTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61083187-A | — | — | None | — | — | JP | disclosed |
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| JP-S6183187-A | FUROXANTHONE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1986-04-26 | — | — | JP | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |