Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246735 | 0.87 | RAB9A (0.64) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL13144514 | 0.83 | MAPT (0.70) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL23163990 | 0.79 | CYP1A2 (0.43) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL1513053 | 0.78 | RAB9A (0.60) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL13297066 | 0.78 | RAB9A (0.59) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL7168897 | 0.78 | MAPT (0.64) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL6872435 | 0.77 | MAPT (0.53) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL27108838 | 0.77 | RAB9A (0.72) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL31341048 | 0.77 | RAB9A (0.57) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL2838513 | 0.76 | RAB9A (0.62) | MAPTRAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402246-B1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0402246-A1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL-UCLAF (FR) | 1990-12-12 | — | — | EP | disclosed |