Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380836 | 1.00 | KDM4E (0.63) | KDM4ELMNAAKR1C3ALDH1A1PKM | |
| SCHEMBL9380318 | 0.91 | KDM4E (0.55) | KDM4ELMNAAKR1C3ALDH1A1BACE1 | |
| SCHEMBL9380325 | 0.91 | KDM4E (0.55) | KDM4ELMNAAKR1C3ALDH1A1BACE1 | |
| SCHEMBL8786625 | 0.90 | KDM4E (0.63) | KDM4ELMNAAKR1C3ALDH1A1PKM | |
| SCHEMBL8786629 | 0.90 | KDM4E (0.63) | KDM4ELMNAAKR1C3ALDH1A1PKM | |
| SCHEMBL9379221 | 0.89 | BACE1 (0.58) | KDM4ELMNAAKR1C3ALDH1A1BACE1 | |
| SCHEMBL9379228 | 0.89 | BACE1 (0.58) | KDM4ELMNAAKR1C3ALDH1A1BACE1 | |
| SCHEMBL25221692 | 0.86 | MAOB (0.53) | KDM4ELMNAALDH1A1BACE1APP | |
| SCHEMBL16076972 | 0.86 | MAOB (0.53) | KDM4ELMNAALDH1A1BACE1APP | |
| SCHEMBL8789901 | 0.84 | KDM4E (0.60) | KDM4ELMNAAKR1C3ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |