Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968453 | 0.83 | ACHE (1.00) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8968773 | 0.81 | ACHE (0.97) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8968393 | 0.80 | ACHE (0.70) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL6921297 | 0.80 | ACHE (0.70) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8969327 | 0.80 | ACHE (0.70) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8969123 | 0.78 | ACHE (0.68) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8969705 | 0.78 | ACHE (0.68) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8968413 | 0.78 | ACHE (0.68) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8969549 | 0.77 | ACHE (0.65) | ACHEBCHEUSP2MEN1ALDH1A1 | |
| SCHEMBL8969681 | 0.77 | ACHE (0.65) | ACHEBCHEUSP2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |