Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533663 | 0.87 | MEN1 (0.48) | MEN1KMT2ASLC22A12LMNAADORA3 | |
| SCHEMBL2754303 | 0.86 | BID (0.47) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL2858513 | 0.82 | DHODH (0.44) | DHODH | |
| SCHEMBL5532401 | 0.79 | DHODH (0.49) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL10422785 | 0.78 | PDE10A (0.48) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL29986186 | 0.77 | PTGS1 (0.46) | SLC22A12LMNAL3MBTL1 | |
| SCHEMBL28459405 | 0.77 | KDM4E (0.50) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL27543370 | 0.76 | DHODH (0.40) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL19138009 | 0.76 | HTT (0.46) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL27541388 | 0.75 | KDM4E (0.44) | DHODHSLC22A12LMNAADORA3NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619819-A1 | 1-ARYLHETEROARYLALKYL SUBSTITUTED-1H-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1994-10-19 | — | — | EP | claimed |