Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907482 | 0.86 | MEN1 (0.54) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL28879008 | 0.82 | TRPV1 (0.49) | DHODHKMT2A | |
| SCHEMBL645855 | 0.81 | KDM4E (0.49) | DHODHKMT2ALMNANAPRTP4HTM | |
| SCHEMBL8548096 | 0.81 | ADORA3 (0.58) | MEN1KMT2ALMNACYP2C19CYP2D6 | |
| SCHEMBL28459405 | 0.80 | KDM4E (0.50) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL9381024 | 0.79 | DHODH (0.43) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL19138009 | 0.79 | HTT (0.46) | DHODHPDE10ATSHRMEN1KMT2A | |
| SCHEMBL7863682 | 0.77 | PDE10A (0.44) | DHODHPDE10AMEN1KMT2ALDHA | |
| SCHEMBL368305 | 0.76 | DHODH (0.47) | DHODHPDE10ATSHRLMNANAPRT | |
| SCHEMBL353204 | 0.75 | KDM4E (0.40) | PDE10AKMT2ALMNANAPRTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855670-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merck & Co., Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006091496-A2 | BENZAZOLE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK & CO., INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| US-4965272-A | EUPOLAURIDINE AND NONTOXIC CARRIER | UNIVERSITY OF MISSISSIPPI, THE | 1990-10-23 | — | — | US | disclosed |
| US-4873250-A | ONYCHINE | THE UNIVERSITY OF MISSISSIPPI (US) | 1989-10-10 | — | — | US | disclosed |