Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545834 | 0.88 | HCAR3 (0.35) | KDM4ESMN1; SMN2HCAR3POLBGAA | |
| SCHEMBL10936850 | 0.74 | TSHR (0.55) | TSHRCYP3A4KDM4EGPR35SMN1; SMN2 | |
| SCHEMBL27768184 | 0.72 | TSHR (0.51) | TSHRCYP3A4KDM4EGPR35SMN1; SMN2 | |
| SCHEMBL4554976 | 0.69 | TSHR (0.60) | TSHRCYP3A4KDM4EGPR35HCAR3 | |
| SCHEMBL2036709 | 0.67 | TSHR (0.62) | TSHRCYP3A4KDM4EGPR35SMN1; SMN2 | |
| SCHEMBL6037509 | 0.67 | TSHR (0.45) | TSHRCYP3A4KDM4ESMN1; SMN2HCAR3 | |
| SCHEMBL12947883 | 0.66 | TSHR (0.51) | TSHRCYP3A4SMN1; SMN2POLBGAA | |
| SCHEMBL11613863 | 0.66 | TSHR (0.51) | TSHRCYP3A4KDM4EGPR35HCAR3 | |
| SCHEMBL11744603 | 0.66 | TSHR (0.47) | TSHRCYP3A4KDM4EGPR35HCAR3 | |
| SCHEMBL7041286 | 0.65 | TSHR (0.53) | TSHRCYP3A4KDM4EGPR35SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586686-A1 | N-HETEROCYCLIC NITRO ANILINES AS FUNGICIDES | DOWELANCO (US) | 1994-03-16 | — | — | EP | claimed |
| WO-1993019054-A1 | N-HETEROCYCLIC NITRO ANILINES AS FUNGICIDES | DOWELANCO (US) | 1993-09-30 | — | — | WO | claimed |